The 2005-06 campaign was a solid year of mid-table consolidation for Piacenza, with the Biancorossi finishing 12th in Serie B. Spearheading the attack was the young striker Daniele Cacia, whose career-best 18 goals proved decisive in a campaign built on consistency under manager Giuseppe Iachini. The season featured a memorable 2-1 derby victory against rivals Cremonese at the Stadio Leonardo Garilli and marked Cacia's emergence as a formidable goalscorer, a defining chapter in the club's modern history.