The 2009 Buffalo Bills season was highlighted by the exceptional performance of rookie safety Jairus Byrd, who led the AFL with nine interceptions and earned a Pro Bowl selection. The team also celebrated the historic 50th anniversary of the American Football League, featuring memorable throwback uniforms and a season-opening victory over the division rival New York Jets. Under interim head coach Perry Fewell, the Bills demonstrated resilience late in the year, securing a notable shutout victory against the Super Bowl-bound Indianapolis Colts.