The 2021-22 campaign saw Sassuolo, under new manager Alessio Dionisi, establish themselves as Serie A's most exciting dark horses, securing an 11th-place finish and reaching the Coppa Italia quarter-finals. Spearheading the Neroverdi's high-scoring attack was the prolific Gianluca Scamacca, whose 16 league goals cemented his breakthrough season, with the campaign highlighted by stunning away victories against giants like Juventus, Inter, and AC Milan.