In the 2021 MLS season, Orlando City SC finished 6th in the Eastern Conference with a 13-9-12 record, accumulating 51 points under head coach Oscar Pareja. The team scored 50 goals and conceded 48 during the regular season. Daryl Dike and Nani led the offense as the top scorers with 10 goals each, while Mauricio Pereyra recorded 10 assists. Although the Lions successfully qualified for the Audi MLS Cup Playoffs, they were ultimately eliminated in the First Round, losing 3-1 to Nashville SC.